четверг, 16 апреля 2015 г.

Anadrol (Oxymetholone) VS Dbol benefits cycle

Oxymetholone (Anadrol) is a very powerful anabolic androgenic steroid of immense capabilities. Generally a bulking steroid, as size promotion is its primary purpose it does possess secondary characteristics well-suited for cutting as well but only in very specific cases and for the average man this type of use will never be implored. As a powerful steroid most will find Oxymetholone (Anadrol) is best used during a bulking cycle at the front end as a kick start to the overall cycle. The most common practice is a 4-6 week run of Oxymetholone (Anadrol) at a dosing of 50mg per day and for many this will be all the Oxymetholone (Anadrol) they will ever need. However, for those who want a little more and these individuals always exist, 100g per day for the same time frame can be successfully administered but there are some important notes. It is important to understand how your body reacts to this steroid before you ever begin a 100mg dose; further, understand the possibility of negative side-effects increase dramatically when the dosing is increased.

Oxymetholone (Anadrol) was used to help with muscle growth in patients with malnourishment and growth problems, in addition, it was given to osteoporosis and anemia patients. In time, it became evident that the side effects of Anadrol are so harsh that some patients with wasting disease developed liver problems and an alternative drug was discovered as a replacement. However, a few decades later, Oxymetholone (Anadrol) resurfaced again to help with HIV/AIDS wasting syndrome.

While 100mg a day will prove to be the maximum dosage that can be safely used, assuming the individual knows what they’re doing, beyond 100mg will often prove to be a waste as Oxymetholone (Anadrol) has been shown to possess a fast diminishing rate when you go past the 100g mark. This simply means doses of 150mg or 200mg and beyond will not produce results greater than 100mg or at least at any noteworthy affect. The same can also be said of total duration; past the 6 week mark the benefits of Oxymetholone supplementation will begin to largely fade. While an individual may indeed pack on as much as 20-30lbs with the steroid the first 4-6 weeks such massive increases will not occur past the 6 week mark.

As is with all anabolic steroids Oxymetholone (Anadrol) does carry with it the possibility of negative adverse side-effects and with this steroid they can be very severe; especially when responsible use is thrown to the wind. Oxymetholone is one of the most hepatic oral steroids on the market; as a 17-aa steroid it is very toxic to the liver but while this is the case with all 17-aa steroids it is more so here. Granted, with responsible use liver damage will often be reversed when use is discontinued but this is assuming responsible sue was implored. Further, as it is well-known for, Oxymetholone (Anadrol) can greatly cause a massive buildup in water retention, so much so that for many the effect can be unbearable. For this reason the use of an aromatase inhibitor (AI) is highly advised. Further, the use of an AI will aid in the prevention of gynecomastia as well, another possible side-effect due to use. It is important to note, regarding water retention more often than not its unbearable nature is brought on by excess carbohydrate consumption. Excess carbohydrates will cause bloat, Oxymetholone (Anadrol) will cause bloat, couple the two factors together and you often have a mess. Learn to control your eating and this problem can be largely avoided when responsible use is followed.

As is easy to see, by its very nature Oxymetholone (Anadrol) serves the primary role of increasing size, however, many competitive bodybuilders supplement with the steroid at the end of a contest prep cycle in order to fill out more efficiently. One must have a full understanding of the steroid to pull off such use without excess water retention being a problem but as the steroids effect on carbohydrate consumption is so pronounced it can have a positive effect when used properly for this purpose.

Like Dianabol, Anadrol doesn’t bind well to the androgen receptor (AR) and is known to exert anabolic effects through non-AR-mediated effects. When compared to Dbol, Anadrol can be a bit harsh and more toxic than Dbol though athletes can avoid this negative aspect of Anadrol by following proper precautions. Both (Anadrol and Dbol) are c17 alpha alkylated, which means athletes should focus on liver protection through N2Guard, Liv52, and other drugs. Dianabol, on the other hand, promotes the sense of well being but athletes can expect an increased risk of male pattern baldness by using Dbol. In addition, Dianabol is well-known for facilitating quality muscle gains without too much of water retention, which means athletes can keep more of the gained lean muscle with Dbol than with Anadrol.

Muscle mass, weight, and strength gains made with Dianabol are fewer as compared to those made with Anadrol. However, Anadrol is a drug that leads to more side effects when compared to Dbol. In order to reap optimum advantages of Dbol, users should use Dianabol at low dosages and for longer periods of time. Anadrol, on the other hand, is best used for a cycle of 2-4 weeks.

The fact that Dbol is cheaper slightly puts it ahead of Anadrol in the battle of Anadrol Vs Dbol but the selection among the two depends on different factors such as expectations from cycle, body statistics, diet, level of workouts, and training and experience. The ideal solution is to take both Anadrol and Dbol in lower dosages for shorter periods of time. A perfect steroid cycle involving these two steroids would be about using Anadrol at weekly dosages of 250-300mg for 2-4 weeks and Dbol for 6 weeks at 200mg every week. Alternatively, you can take Anadrol at 50mg every day and Dianabol 30mg every day for four weeks.

понедельник, 6 апреля 2015 г.

The adrenergic agonist Clenbuterol by Accordo RX

The adrenergic agonist, Clenbuterol is one of the most popular weight and fat loss drugs. Because of its steroid-like results, the weight loss drug (also known as Clen) is commonly used by sportsmen, especially those in body building and participate in weight-related categories.

One of the biggest advantages associated with use of this weight and fat loss drug is that it can improve ability to the body to carry more fresh oxygen than ever, which further promotes nitrogen retention and protein synthesis. Moreover, Clenbuterol is second to none for increasing the rate at which fat is reduced besides promoting cardio exercise potential of the body.

In addition to that, use of Clen is not related to side effects that are common with anabolic steroids and performance enhancing drugs, especially harsh or aromatizable steroids. This also means that Clenbuterol users can be relieved of estrogenic side effects such as oily skin, acne, gynecomastia and bloating in the first place itself.

Clenbuterol use is also related to promotion of nearly permanent muscle mass gains and a slight increase in temperature of the body that proves beneficial in losing “stubborn and stored” fat. Clenbuterol cream, Clenbuterol injections, and Clenbuterol gels can even be used for targeting beta-2 receptors that stimulate muscle growth and more storage of protein in the muscles. The use of Clen cream, gel, and injections is also associated with breakdown of the protein stored in the muscle cells and redirecting fat loss in areas to be emphasized during the fat loss plan. One of the biggest advantages of this fat and weight loss drug is that it helps users lose body fat or weight and gain muscles at the same time besides helping them benefit from spot reduction to emphasize on specific body areas or parts with excess fat.

When used in doses of 60-140 mcg per day by men and 40-120 mcg per day by women, Clenbuterol exhibits its true potential. It is worthwhile to note that doses should start and end low (60 mcg per day for men and 40 mcg per day for women) during a Clenbuterol only cycle. Moreover, the doses should be slowly increased by 20 mcg per day till the maximum dosage is reached (140 mcg per day for men and 120 mcg per day for women) and then reduced by 20 mcg per day to end low (60 mcg per day for men and 40 mcg per day for women). In other words, a Clenbuterol only cycle for men would be in the order: 60mcg, 80mcg, 100mcg, 120mcg, 140mcg, 120mcg, 100mcg, 80mcg, and 60mcg and a Clenbuterol only cycle for women would be in the order: 40mcg, 60mcg, 80mcg, 100mcg, 120mcg, 100mcg, 80mcg, 60mcg and 40mcg.

There are two major parameters that the user has in mind while choosing a steroid. First is his goal in the form of muscle and strength gains and second is his concern about becoming prone to minimum side effects after steroid use. It is a known fact that steroid use is an imperative feature of muscle building. Hence choosing the right steroid which gives you optimum results is a must.

Clenbuterol, commonly referred to as Clen, is a sympathomimetic amine and a bronchodilator largely employed as a drug used for treating respiratory illnesses. It stimulates the aerobic capacity of the body and is an effective thermogenic compound also used for stimulating the central nervous system and oxygen transportation mechanism in the body. It is chemically identified as (RS)-1-(4-amino-3, 5- dichlorophenyl)-2-(tert-butylamino) ethanol and is found to be structurally as well as pharmacological similar to epinephrine and salbutamol.

When Clenbuterol is administered in the blood, it reaches the beta-2 receptors present in it and reacts with them to increase the metabolic rate of the body. This causes the cellular heat of the tissues to increase which stimulates the breakdown of triglycerides to form free fatty acids. In this entire process, the excess amount of heat produced often increases the temperature of the body. Hence people ingesting Clen in their steroid cycle should be prepared to undergo high body temperature for some period. Ideally people do not feel any discomfort in this phase but under any circumstances if the heat becomes too much to bear, then one must immediately see a physician. Another major advantage of Clen intake is enjoyed by both bodybuilders as well as sports persons as it helps in gaining the added strength needed by athletes in their per-competition phases. The only thing that needs to be kept in mind is that Clen can be detected in the body up to 4 to 6 weeks after the steroid cycle is over. Thus those taking the drug in the pre-contest period should plan its administration accordingly.

Since use of Clenbuterol can lead to loss of potassium in the body, it is best to use 200-400 mg of potassium tablets or 3-4 apples and orange per day throughout the Clenbuterol only cycle. Users of this fat loss drug are advised to abstain from using it after evening as Clen use immediately before retiring for the bed may lead to insomnia. In order to control the levels of prolactin, Clenbuterol users also include T3 Cytomel in their cycle. It is also recommended to consume seven to nine glasses of water a day to avoid dehydration and use Clen in a 2-day on and 2-day off or 3-week on and 3-week off cycle.

Like all prescription drugs, the use of Clenbuterol should always be recommended by a qualified medical practitioner and such recommendations should always be made after complete and careful analysis of medical reports and history. People having an existing allergy to the weight loss drug should avoid making use of it. Moreover, the drug should always be purchased from a legal steroid store or pharmacy with a prescription and must be used only for the specified purposes and as per directed. This is because Clenbuterol abuse or use of low grade Clen can lead to side effects such as difficulty in breathing, gastrointestinal irritation, myocardial infarction, skin rash, urticaria, diaphoresis, nausea, tightness in the chest, vomiting, dizziness, depleted phosphate levels, dry mouth, insomnia, muscular shivering, cardiac hypertrophy, palpitation, potassium depletion, loss of concentration, frequent mood swings, and drowsiness.

Abuse of Clenbuterol may also lead to increased blood pressure, muscle cramps, excessive sweating, heartburn, face flushes, tremors, and restlessness. People who are already administered with Antibiotics, Accutane, oral 17-alpha-alkylated steroids or hepatotoxic (toxic to liver) elements should not make use of the weight loss drug, unless otherwise clearly specified by a medical practitioner. Moreover, Clen use is not advised to those suffering from hyperthyroidism, tachycardia, tachyarrhythmia, heart or thyroid diseases, high blood pressure, coronary artery disease, congestive heart failure, prostatic hypertrophy, urinary retention, glaucoma, ischemic heart disease, myocardial infarction, and hypertrophic obstructive cardiomyopathy. Clenbuterol is also not recommended to breastfeeding or lactating women and children.

четверг, 2 апреля 2015 г.

The most popular drug Equipoise

Equipoise has come a long way to become one of the most popular and recommended bodybuilding drugs after being initially developed as a veterinary anabolic steroid. Equipoise (also known as Ganabol, Boldenone and Ultragan) is a highly anabolic and moderately androgenic steroid. Equipoise is generally cheaper than Deca Durabolin and is commonly used to replace Deca without losing on the benefits that may have been offered by Deca in most cycles. One of the biggest benefits of Equipoise is that its use is associated with very little amount of water retention and aromatization. Moreover, use of this performance enhancing drug is associated with an ensuing increase in appetite and this is a good enough reason for sportsmen and others to include Boldenone in a bulking steroid cycle. This anabolic steroid is as anabolic as testosterone and is half androgenic as testosterone. Equipoise can be effectively used for both cutting and bulking cycles because of its well-balanced effects. This steroid is not hard on the hair line as it gets converted to DHN (a very mild androgen in comparison to DHT) via 5- alpha reductase though only a small amount is actually converted.

Boldenone is metabolized by aromatase to estradiol, but to a lesser a degree than testosterone. It also is metabolized by the 5-AR enzyme, in this case to 17b-hydroxyandrost-1-ene-3-one, commonly but incorrectly called “1-testosterone” and sometimes called dihydroboldenone. This molecule’s potency is similar to that of Boldenone, so the molecule is neither potentiated or deactivated by the 5-AR enzyme and therefore that metabolism is unimportant

The mild nature and steady gains produced by Equipoise are complemented with an increase in appetite and the ability to eat more food while making efforts to gain weight in the off season makes it an instant hit with sportsmen. In addition to these advantages, Equipoise use is also linked with enhancements in terms of the number of red blood cells and the percentage of red blood cells (hemoglobin and Hematocrit), which further translates into greater “pumps” during intense workouts. Furthermore, body strength and muscle mass gains made with this steroid are more pronounced with Equipoise than with any other steroid or performance enhancing drug. Since Boldenone stimulates the release of EPO (erythropoietin) in the kidneys, sportsmen using the steroid can expect an increase in count of red blood cells (production of erythrocytes). Since erythrocytes are oxygen carriers in the body, a higher maximal oxygen capacity is produced with an increase in their concentration that leads to improved performances because of a delay in the onset of fatigue, which results in buildup of lactic acid. Use of this performance enhancing drug is also associated with moderate reductions of HPTA function and promotion of solid, meaty muscle fiber when complemented with strength exercises and healthy lifestyle.

It can be stacked with Winstrol (Stanozolol), Oxandrolone, Testosterone enanthate, Testosterone Cypionate and Testosterone Propionate in an anabolic steroid cycle of six to eight weeks for promoting anabolic activity while keeping estrogenic side effects. The reason why Boldenone is commonly stacked with testosterone is because this would negate any libido changes that may be experienced by a user and a combination of Equipoise and Testosterone is second to none for experiencing dramatic increases in terms of lean body mass. Boldenone can be used for long periods of time during extensive cycles since Boldenone is not hepatoxic to any serious extent. It is also stacked by some sportsmen with Trenbolone Acetate, Halotestin or Winstrol during a cutting cycle to experience solid muscle density and hardness gains. The steroid may even be stacked with Oxymetholone (Anadrol) or an injectable testosterone like Sustanon 250.

If that was not all, anabolic steroids and performance enhancing drugs that tend to raise liver values like 17 alpha alkylated steroids can be stacked with Boldenone as liver toxicity is not or rarely associated with the compound. Male bodybuilders often use Equipoise in doses of 200-600 mg every week for about twelve to twenty weeks as per their objectives and female bodybuilders use it in doses of 50-125 mg every week for eight to twelve weeks. The minimum dose is between 300-400 mg per week for males and women can experience results of Boldenone at doses ranging from 50-150 mg per week for less experienced users. A proper post cycle therapy (PCT) with HCG and Clomid/Nolvadex is highly recommended after a waiting time of around two or three weeks before the PCT can be started so that Equipoise can be cleared from the body to make the cycle therapy more effective. An anti-aromatase such as Cytadren or Arimidex may even be used to make the cycle more tolerable. In order to get the best out of Boldenone, users should emphasize on a diet high in protein and calories, along with a proper training regimen and must use the anabolic steroid as directed. The use of this steroid should always be made for legal purposes and under medical supervision. By doing this, users can expect to add quality lean muscle on a consistent basis throughout an anabolic steroid cycle.

The abuse or use of low grade Equipoise can cause side effects such as negatively-affected lipid profile, virilizing effects in women, high degree of water/salt retention, gynecomastia, increased hair growth, acne, aggravation of male pattern baldness, and sexual side effects. Equipoise users can expect the drug producing detectable metabolites in the urine several months after use because of the characteristics of high oil solubility of long chain esterified injectable steroids. When used in an injectable form, users should make it a point to rotate injection sites on a regular basis and follow healthy administration practices so as to avoid irritation or infection and staying away from abscess formation and sharing of needles.

вторник, 24 марта 2015 г.

Structure of Dostinex (Cabergoline) and its effect in cycles with steroids

Dostinex (Cabergoline) is a dopamine agonist. Dopamine is a chemical, found in the brain, which transmits nerve impulses and is involved in the formation of epinephrine.  Dopamine is also released by the hypothalamus, and hormone can inhibit the release of prolactin from the anterior lobe of the pituitary, so given all the bad things that we have already seen to be a result of excess. If you use anabolic steroids, Dostinex will help you reduce the chance of any of these prolactin related side-effects. It has actually been shown in numerous studies to have a very high success rate in lowering prolactin and prolactin related conditions and side-effects.

In fact, for management of hyperprolactinemia and it’s symptoms, Dostinex is the preferred treatment in terms of effectiveness as well as having very few undesirable side effects.  It does this very well for both men and women, it should be noted almost identically actually.

Since it lowers prolactin very efficiently, Dostinex will even get rid sexual dysfunction caused by excess prolactin (which is highly correlative with the use of certain steroids like the Nandrolones and Trenbolones (Deca and Tren). This is great news for everyone who loves Tren and Deca, because those two steroids are really great additions to almost any cycle- but many people avoid using them because of the possibility of them causing impotence.

Using Dostinex will allow you to include steroids like Tren and Deca in any cycle- and even combine them in the same cycle- without worrying about sexual dysfunction. In fact even if you aren’t experiencing any sort of sexual dysfunction, Dostinex will shorten the time you need to recover and gain an erection between orgasms, and can significantly enhance all parameters of sexual drive and function.

Of course you can actually use Dostinex safely for an extended amount of time (many studies go on for months if not years, and its efficacy and safety are well documented), but women need to be more careful than men, and certainly need to discontinue using it if they’re pregnant or trying to conceive. Dostinex can help you, the average steroid user, by combating gyno-like effects, as well as galactorrhea, and sexual dysfunction.

Tthis structure which makes it very interesting to us. Dostinex as you already know is what’s known as a dopamine “agonist”- or substance that triggers a response in a specific body tissue or group of cells by binding to specific receptor on or inside the cells, as if it were actually the bodily substance that usually binds to that receptor. Probably the one that most people are familiar with, with regards to agonists is ephedrine, which is an andrenergic agonist. This is why ephedrine makes you feel “wired”…it “feels” like adrenaline to your body. Cabergoline is a dopamine agonist…which makes it “feel” like dopamine to your body.

So what does that mean? Well, in the brain, dopamine helps control the flow of information from other areas of the brain. So a dopamine agonist will help you process information more quickly, and possibly improve your memory also. Some athletes use Dostinex because it helps them learn new motor skills more quickly and thus they can learn new techniques or plays at a faster rate than their competition; needless to say this gives the athletes using Dostinex a huge advantage over their competition. This ability to work on your bodies information pathways and nervous system are doubtless why it’s been successfully been used to fight Parkinsons disease.
In fact, when you don’t have enough dopamine, you may even have difficulty concentrating, low dopamine levels have also been cited as a possible underlying cause for Attention deficit disorder (ADD) and Attention deficit/ Hyperactivity disorder (ADHD). In fact, many several medications used to treat ADD and ADHD will also serve to stimulate dopaminergic, and this could be one of their possible mechanisms of action.

Interestingly, since this “happy” effect is felt when you are satiated from food, it’s highly possible that Dopamine agonists will cause you to feel “full” more often and decrease desire for food without the discomfort that dieting usually brings. Dopamine is released when you eat a nice big meal so a dopamine agonist like Dostinex may make you not want to eat as much, and help you feel full even if you don’t eat enough. Dostinex, therefore, may be of great interest to precontest bodybuilders and other dieters, who want to avoid some of the discomfort and anxiety that calorie restriction can bring. Dostinex is, of course, neither physically nor mentally addictive, but since it is a dopamine agonist, its users often experience an enhanced positive sense of well being. So besides helping with all of the things discussed earlier, Cabergoline will also just make you feel damn good.

вторник, 17 марта 2015 г.

Benefits of Deca Durabolin Cycles and Doses

The benefits of Deca Durabolin are very simple but as this is a very powerful anabolic they are very great. By understanding what Nandrolone does understanding the benefits of Deca Durabolin should be fairly simple, increased muscle mass and increased strength. While these are the two most prominent effects there is the added benefit of joint relief as well by means of a secondary nature; for this reason many athletes will supplement with Deca Durabolin even when not in a gaining phase in order to obtain such relief.

To give you an idea of how powerful this hormone is even small therapeutic doses can cause large increases in weight by increasing lean mass and this is achieved largely due to its nitrogen retention abilities.
Those who supplement with Deca Durabolin will find their muscle holds a far greater amount of nitrogen than without; as we understand being in a state of positive nitrogen retention is highly anabolic. This state of being can lead to vast although slow increases in muscle tissue and while that can lead to mass, coupled with increased collagen synthesis we experience a nice buildup in strength as well. Of equal importance if not even greater is the effect Nandrolone has on the production of IGF 1, a very powerful anabolic hormone in its own right belonging to the peptide class. While these potent anabolic qualities are very apt towards building mass and increasing strength they prove due to their action to readily promote a greater metabolic rate this simply means we are able to build a larger, yet leaner and more powerful physique as you can see Nandrolone is one amazing hormone.

All steroidal hormones carry with them possible negative side-effects, as do all medications, steroidal and non-steroidal alike, Deca Durabolin makes no exception. By far the most prominent side-effect is testosterone suppression, while all anabolic steroids will suppress natural testosterone production to one degree or another Deca Durabolin will do so in a far more pronounced manner. One dosing of this Nandrolone will result in complete testosterone suppression, even a very low dose will have this effect. For this reason it is very important to supplement with testosterone when we supplement with Deca Durabolin, failure to do so will result in leaving the body completely testosterone deficient. Most will find a 2:1 ratio of Test: Deca to be sufficient but for some the need for testosterone to be slightly higher than this will prove to be a reality.

While this hormonal compound does not aromatize to high degree some aromatizing effects commonly associated with anabolic steroids can occur; while these are largely dose dependent ones sensitivity also comes into play. Further, when used for performance enhancing purposes these effects will assuredly be a reality as the dosing will necessarily be higher than simple therapeutic use in order to achieve a desired end result. Further, because Deca Durabolin is a progestin by-which it will raise progesterone levels in the body, coupled with even a slight aromatase effect this can lead to Gynecomastia and excess water retention most commonly but this can easily be alleviated by the use of a quality aromatase inhibitor such as Arimidex or Letrozole.

As we now readily understand Deca Durabolin is simply Nandrolone with the Decanoate ester attached and there are many other Nandrolone based steroidal compounds. While Deca-Durabolin is the most common and popular form Durabolin is a close second, especially in recent years. Durabolin is simple a Nandrolone hormone attached to the Phenylpropionate ester, a much shorter ester, thereby bringing benefit faster yet not as long lasting. The mode of action regarding the hormone Nandrolone does not change due to one form or the other being used, only the ester is different. Regardless of which form you use for each 100mg your apply, while Durabolin will provide slightly more active Nandrolone per mg than Deca Durabolin due to the total mass of the Phenylpropionate ester being less than the Decanoate ester the difference is so slight it is meaningless, the same benefits are to be obtained with either form as the same active hormone is present in both. This is important because for years many misconceptions have led many to believe these two compounds differ greatly when the opposite is true. However, we must admit there is a slight difference as Durabolin or NPP as it’s commonly called seems to produce less water retention than it's brother Deca Durabolin.

Because it is so apt for strength and size most will use Deca Durabolin during a bulking cycle further, as water retention can be a problem when this steroid is used this makes periods of bulking or gaining the optimal time for use. However, as we’ve discussed excess water retention can be controlled through the use of a quality aromatase inhibitor and for this reason, as this is a powerful anabolic, many competitive bodybuilders will include Deca Durabolin in their contest prep cycles. In most cases this will be done during the front end of the contest prep cycle in an effort to preserve muscle tissue and hold on to strength. However, many will run a low dose of the steroid almost the entire length of their contest prep in order to maintain joint comfort as discomfort can become quite serious when body-fat levels drop to very low levels.

For the majority, bulking will be the primary mode of use and as this is a very slow acting but long lasting steroid and as it is generally well-tolerated by most who use it, necessarily use will extend into several months if benefits are to be enjoyed. Generally Deca Durabolin will need to be administered for at least 8 weeks with 12 weeks being optimal and 16 weeks being safe and highly effective for most individuals. Shorter duration will prove to be useless as it will take a good 4 weeks for the active benefits to begin to show making 4-6 week runs of the compound utterly useless. Most will find a dose of 200mg per week to be the minimum dosing to obtain benefits associated with growth, although a mere 100mg per week is often all that is used if joint relief is the primary concern. While 200mg is enough to spur growth most will find 400mg a week for approximately 12 weeks to be nearly a perfect dose and time frame for Deca Durabolin use. Keep in mind, you must ensure you take enough testosterone with your Deca Durabolin to ensure you keep enough active testosterone flowing in the body. For those who are looking for more of a bump 600mg per week can be successfully used, however, this is only recommended for those who have used the hormone before and understand how their bodies will react and how well they will tolerate this powerful Nandrolone even so, many will find 400mg to be all they ever need regardless of how experienced they are.

среда, 11 марта 2015 г.

Testosterone Cypionate and Post Cycle Therapy

Testosterone Cypionate is one of the many synthetic versions of testosterone. It is the second most popular testosterone variant after another synthetic version, Testosterone enanthate. It is usually delivered to the body in the form of an oil-soluble intramuscular injection. In this form, it is called Depo - Testosterone.

In powder form, Testosterone Cypionate is creamy white with nearly no odor. It is stable in air and dissolves in alcohol, vegetable oil, ether, and chloroform but does not dissolve in water. Testosterone Cypionate (GP Test Cyp) is basically esterified testosterone, so it has increased lipid solubility. Nearly 90% of an injection is excreted in urine as sulfuric acid and glucuronic acid conjugates of testosterone and its related metabolites. It is not recommended for individuals under 18 years of age. Also, it should not be used by women, especially those who are pregnant, because it may cause damage to the fetus.

Testosterone Cypionate (GP Test Cyp) is used as a replacement for natural testosterone in men, who are suffering from low testosterone levels. It is a prescription drug and legally speaking, it can be given only when testosterone deficiency has been confirmed through symptoms or blood tests. The body cannot store testosterone, which means if you are suffering from a deficiency you will have to continue taking these injections at regular intervals and in proper doses. Apart from individuals who are suffering from low levels of testosterone, it is also used by many athletes and body builders for its anabolic properties.

Testosterone Cypionate can help promote fat loss, increase sex drive, help in gaining muscle mass, and increase the density of bone. Like testosterone, Testosterone Cypionate (GP Test Cyp) also has an anabolic and androgenic rating of 100. It has a long half-life and a slow release rate of about 8-10 days. It is similar to Testosterone Enanthate in its effect and you can even switch between them. Nearly 14 million men in the US, above the age of 45 years, have testosterone deficiency. It can lead to a loss of strength and muscle mass, diminished sexual performance and libido, body fat increase, and low levels of energy. Low testosterone levels can also lead to diabetes, osteoporosis, Alzheimer's disease, and more. Like all anabolic steroids, the more you take in Testosterone Cypionate, the more will be the rewards, but when you do this, the incidence of side effects also increase. It can be bought in two strengths – 100mg and 200 mg. Since it is absorbed slowly, you can inject it at an interval of two or four weeks. Many factors determine how much Testosterone Cypionate (GP Test Cyp) a person can take safely. These include body weight, medical conditions, and the intake of other medicines. Usually, an adult male can take a dose of 200 mg of Testosterone Cypionate (GP Test Cyp) every fourteen days. The gluteal muscle in the buttocks is the usual site of injection.

Some individuals split the intake of Testosterone Cypionate into smaller but equal doses, which are then injected over a period of time. The advantage of this method is that it keeps the level of the steroid in the blood at a peak and it also controls the side effects that may result from using large doses. Smaller doses also mean that the body has to deal with fewer steroids at one time. Regardless of what dose you use, you will find that Testosterone Cypionate (GP Test Cyp) is well tolerated by the body and you can use it for long cycles. Some individuals even run Testosterone Cypionate cycles of 12 weeks to 16 weeks.

Note that you may need to have a Post Cycle Therapy plan in place before you end your Testosterone Cypionate (GP Test Cyp) cycle. But again, this depends on the length of the off-period (the time when you will not be taking any steroids). If this off-period is more than 10 weeks, you will need Post Cycle Therapy.

Increasing your dosage suddenly might actually slow down results. This is because the body converts any excess testosterone into estrogen, by a process called aromatase. It is a natural reaction and the body does it so that a normal hormone level can be maintained. So, taking large doses is not a good idea.

Women are advised not to take Testosterone Cypionate because it has strong androgenic properties. After all, testosterone is primarily a male androgen. But on the other hand, women can also have low testosterone levels and they may benefit from taking anabolic steroids. In this case, the dosage should be very low and should be carefully watched out for.The side effects of Testosterone cypionate can be easily controlled. It is not guaranteed that these side effects will even occur. It will all depend on the dose that you take, whether you are genetically predisposed to them, and your current health. Here is little more about the side effects that can be expected.

Testosterone Cypionate (GP Test Cyp) is another form of testosterone, so there will be aromatase activity. As the level of estrogen in the blood rises, it can lead to water retention and gynecomastia. So, many body builders do not prefer Testosterone Cypionate (GP Test Cyp) for gaining muscle mass. When they do take it, they will stack it with other anabolic steroids. To deal with gynecomastia, many individuals take SERMs or selective estrogen receptor modulators like Tamoxifen Citrate or aromatase inhibitors like Anastrozole. Side effects like hair loss (in men who have a predisposition to male pattern baldness), acne, and prostate enlargement have also been noticed after the dosage of Testosterone Cypionate.

четверг, 5 марта 2015 г.

Benefits of Testoviron Stack

Testoviron is a blend of two different products, namely testosterone with the propionate (short) ester attached, and testosterone with the Enanthate (long) ester attached. Testosterone is usually attached to an ester (i.e. when you buy testosterone propionate, or Enanthate the components of this particular drug, you are buying testosterone with a Propionate ester attached and testosterone with an Enanthate ester attached, both in the same milliliter of drug). These esters determines how long it takes your body to dispose of the testosterone, and propionate is the shortest ester commonly available with a testosterone base (of course, testosterone suspension has no ester), whereas Enanthate is the longest generally available with a testosterone base. Within your body, there are enzymes, called esterases, which have the function of removing the ester from steroids, and leaving you with just the steroid molecule with the ester cleaved off. Depending on how heavy the ester chain is, that determines how long it takes the esterase to remove it.
Testoviron is a blend of two different products, Testosterone Propionate (short ester) and Testosterone Enanthate (long ester).

Testosterone is responsible for promoting health and well-being through enhanced libido, energy, immunity, increased fat loss, gaining and maintaining lean muscle mass, preventing Osteoporosis (loss of bone density) and possible protection against heart disease. Testosterone is also responsible for normal growth and development of male sex organs and maintenance of secondary sex characteristics. Secondary sex characteristics are specific traits that separate the two sexes, but are not directly part of the reproductive system, for example: chest and facial hair, a distinguished jaw line, broad shoulders and increased muscle mass. Testosterone binds to the Androgen Receptors (AR), which thus causes accelerated muscle gain, fat loss, and muscle repair and growth. These mechanisms are stimulated by activation of the Androgen Receptors (either directly or as DHT).

There are many possible side-effects associated with its use. This product also has a high level of aromatization into estrogen and coverts to DHT (dihydrotestosterone) as well. Also, supplementing Testosterone to your body will result in the shutting down of the body’s natural production of the hormone. The severity of side effects depend mostly on the levels and duration of circulating free testosterone, and its conversion to substrates. Testosterone’s anabolic/androgenic effects are dependant upon dosage, the higher the dose the higher the muscle building effect (and often, it’s side effects). Testosterone promotes aggressive and dominant behavior.

Testosterone’s anabolic/androgenic effects are dependant upon the dose administered; usually the higher the dose, the better the results. In a study done on Testosterone Enanthate in this case), a dose as high as 600 mg’s (per week) produced better results in subjects compared to those who received all of the lower doses. At the highest dose, 600 mg/week, the greatest results were achieved in comparison to any of the lower doses studied. The highest fat loss, most muscle growth, and increased size and strength were achieved at the higher dose. In the same study, HDL cholesterol was lowered and the subjects experienced acne. There was roughly a 15% gain in Lean Body Mass from 20 weeks of 600mgs/week of Testosterone therapy.

Overall, the most common report by subjects using testosterone was immense gains in strength. Alterations in size, shape, and appearance of the muscle were reported.

Due to stimulation of the Androgen Receptors (either directly or as DHT), accelerated muscle gain, fat loss, increased muscle repair and growth was experienced. Testosterone binds to the A.R. on fat cells; therefore, adipose (fat) tissue can be broken down more readily while new fat formation is prevented. Since the body is building muscle at an accelerated rate, more ingested food is shuttled directly to the muscle tissue (this is known as nutrient portioning) and away from fat. This is another indirect effect of testosterone on fat loss. Testosterone also promotes glycogen synthesis, which is activated by insulin in response to high glucose levels. Glycogen provides fuel to the muscle, therefore endurance and strength increases were reported during severe muscle breakdown in intense training and workouts.

Testosterone also converts to both Estrogen and Dihydrotestosterone (through 5a-reduction). Most of the side effects people experience with testosterone use is actually from it’s conversion to these two substrates. Hair loss, water retention, acne, and other side effects are possible with use of this drug.

Testoviron is actually a very decent anabolic, and is very rarely counterfeited any longer. Basically, what we’re looking at is a nice pre-mixed blend of Testosterone with a long ester (Enanthate) and a short ester (Propionate). If I were personally to make my own test blend to use every other day, it would most likely be something very similar to Testoviron.

The short ester will give you a nice spike in testosterone levels, albeit one that decays very quickly, while the longer ester will allow a very slow decay in blood plasma levels.

One of the primary advantages to this version of testosterone is that it is very rarely faked because products like Sustanon (a 4 ester blend) fetch a higher price, and if you’re going to counterfeit an amp, it may as well be the one which will earn you the highest profit for your trouble. This is why we never see counterfeit “Sten” amps (a very low dosed preparation of testosterone) and this basically holds true for Testoviron as well.

Testoviron Stack:

What stacks well with Testoviron? Well, since its a testosterone with both a short and long acting component, I suppose the answer is everything and nothing. Since its got a short ester in it, you would have to inject it every other day, so you may as well run another short acting drug with it (Trenbolone Acetate, or whatever). However, since its got a long acting component to it, you may consider using a longer acting drug with it (Deca or Eq), the downfall here is that you dont get the full benefit of shooting test prop alone (less water retention, etc...) but you still have to shoot as frequently as if you were only using prop. The testosterone Enanthate is long acting, but you're still going to be shooting this compound every other day to make use of the Propionate component. Thus, the advantage of testosterone Enanthate (reduced shooting frequency) is negated. Many peoples favorites are Equipoise (Boldenone Undeclyenate) or Deca (Nandrolone Decanoate), but really, anything will stack well with Testoviron. Tren (Trenbolone Acetate), Masteron and Winstrol are also favorites for many on a cutting cycle, and its important to note that a product to fight water-retention and other estrogenic sides would be warranted if Testoviron were used for a cutting cycle.

Finally, its worth noting that sometimes a strategy known as "front loading" is employed with products like this one, since it contains both testosterone Propionate, and Enanthate. This is where double or triple the intended dose for the cycle is injected for the first two weeks and the Propionate ester gives a very quick rise in blood plasma levels of testosterone, and then the Enanthate ester is relied on for a more even blood level in the ensuing weeks. The reasoning behind this is presumably to get the blood levels of the drug up quickly in the hopes of seeing results more quickly, and then have the blood levels even out and stay constant.

пятница, 30 января 2015 г.

Nolvadex, Clomid and HCG in Post Cycle Therapy


Most anabolic steroids, especially the androgen's, cause inhibition of the body's own testosterone production. When a bodybuilder comes off a steroid cycle, natural testosterone production is zero and the levels of the steroids taken in the blood are diminishing. This leaves the ratios of catabolic : anabolic hormones in the blood high, hence the body is in a state of catabolism, and, as a result, much of the muscle tissue that was gained on the cycle is now going to be lost.

Clomid stimulates the hypothalamus to, in turn stimulant the anterior pituitary gland (aka hypophysis) to release gonadotrophic hormones. The gonadotrophic hormones are follicle stimulating hormone (FSH) and luteinizing hormone (LH - aka interstitial cell stimulating hormone (ICSH)). FSH stimulates the testes to produce more testosterone, and LH stimulates them to secrete more testosterone. This feedback mechanism is known as the hypothalamic-pituitary-testes axis (HPTA), and results in an increase of the body's own testosterone production and blood levels rise, to, in part, compensate for the diminishing levels of exogenous steroids. This is vital to minimize post cycle muscle losses. Not all steroids do cause shut down of the feedback mechanism. Everyone is different and you must also take into account how long you have been using a certain steroid and at what dose in order to determine if you need Clomid or not.

Clomid also works as an anti-oestrogen. As it's a weak synthetic oestrogen, it binds to oestrogen receptors on cells blocking them to oestrogen in the blood. This minimizes the negative effects like gynecomastia and water retention that may be a result of oestrogen that has aromatised from testosterone.

It's effect as an anti-oestrogen are quite weak though, and it should not be relied upon if you are going to be using androgenic steroids that aromatise at a rapid rate, or if you are pre-disposed to gynecomastia. Arimidex and Nolvadex (Tamoxifen) are far more effective anti-oestrogens.

Clomid does not, as is often thought, stimulate the release of natural testosterone, but rather works at reducing the oestrogenic inhibition caused by the steroid cycle. It does this in a similar manner to the way it and Nolvadex block oestrogen receptors in nipples to combat gyno development, i.e. by blocking the oestrogen receptors in the hypothalamus and pituitary thus reducing the inhibition from the elevated oestrogen. This allows LH levels to return to normal, or even above normal levels, and in turn, natural testosterone levels to also normalize.

When we use anabolic steroids, the level of androgen's in the body rises causing the androgen receptors to become more highly activated, and through the HPTA, a signal tells our testes to stop producing testosterone. During a cycle the body has far higher than normal levels of androgen's and as long as this level is high enough, Clomid will not help to keep natural testosterone production up. It will be almost all but completely shut off, in theory.

Some heavy androgen users, however, do advocate a small burst of Clomid mid-cycle, though it must be hard for them to say if it really of any benefit, due to the amount of gear they are using. Therefore, the only purpose of Clomid during a cycle is as an anti-estrogen.

When To Take Clomid:

The correct time to commence Clomid depends on the type and cycle of steroids you have been using. Different steroids have different half-lifes (indicates the time a substance diminishes in blood), and Clomid administration should be taken accordingly.

As we have seen above, Clomid taken when androgen levels in our blood are still high will be a waste. It is crucial to wait for androgen levels to fall before implementing our Clomid therapy. However, if taken too late we could possibly lose gains.


How to take Nolvadex for PCT:
As an alternative to Clomid, which has been reported to have led to unwanted side effects such as visual disturbances in some users, Nolvadex can be employed. Nolvadex is a trade name for the drug Tamoxifen. Like Clomid, the half life of Nolvadex is relatively long enabling the user to implement a single daily dosing schedule. Administration would start as per the timescales outlined above and the duration would be identical to that of Clomid.

Typically, for a moderate-heavy cycle, the following dosages would be used:
Day 1 - 100mg
Following 10 days - 60mg
Following 10 days - 40mg

Occasionally, heavier cycles containing perhaps Nandrolone (Deca) or Trenbolone which by definition are particularly suppressive of the HPTA, may require a slightly longer therapy. Likewise, more modest/shorter cycles may require lower dosages, perhaps dropping each by 20mg per day.

Some users like to use both Clomid and Nolvadex in their PCT in an attempt to cover all angles. An example of the dosages involved might be:

Day 1 - Clomid 200mg + Nolvadex 40mg
Following 10 days - Clomid 50mg + Nolvadex 20mg
Following 10 days - Clomid 50mg or Nolvadex 20mg

Of course, the examples provided are not set in stone and may be adjusted depending on the factors outlined above and individual variances.

How using HCG:
HCG stands for Human Chorionic Gonadotrophin and is not a steroid, but a natural peptide hormone which develops in the placenta of pregnant women during pregnancy to controls the mother's hormones. (Incidentally, this is the reason you may hear of people testing for growth hormone (HGH) with a pregnancy testing kit.

Its action in the male body is like that of LH, stimulating the Leydig cells in the testes to produce testosterone even in the absence of endogenous LH. HCG is therefore used during longer or heavier steroid cycles to maintain testicular size and condition, or to bring atrophied (shrunken) testicles back up to their original condition in preparation for post-cycle Clomid therapy. This process is necessary because atrophied testicles produce reduced levels of natural testosterone, this situation should be rectified prior to post-cycle Clomid therapy.

HCG administration post-cycle is common practice among bodybuilders in the belief that it will aid the natural testosterone recovery, but this theory is unfounded and also counterproductive. The rapid rise in both testosterone, and thus oestrogen due to aromatisation, from the administration of HCG causes further inhibition of the HPTA (Hypothalamic/Pituitary/Testicular Axis - feedback loop discussed above); this actually worsens the recovery situation. HCG does not restore the natural testosterone production.

The typically observed dosing of 2000 to 5000IU every 4 to 5 days causes such an increase in oestrogen levels via aromatisation of the natural testosterone that this has been responsible for many cases of gynecomastia.

Smaller doses, more frequently during a cycle will give best overall results with least unwanted side effects. Somewhere between 500IU and 1000IU per day would be best over about a two-week period. These doses are sufficient to avoid/rectify testicular atrophy without increasing oestrogen levels too dramatically and risking gynecomastia. This dosing schedule also avoids the risk of permanently down-regulating the LH receptors in the testes.

It is important for the HCG administration to have been completed with 6 or 7 clear days before the onset of PCT in order to avoid inhibition of the Nolvadex and/or Clomid therapy. Also, a small daily dose (10-20mg) of Nolvadex would normally be used in conjunction with HCG in order to prevent oestrogenic symptoms caused by sudden increases in aromatisation. Clomid and/or Nolvadex are more effective than HCG post cycle, but some long-term users like to use HCG during a cycle, or to prepare the testes for Clomid and/or Nolvadex therapy.